The main objective of this course is to provide the students the basic knowledge, Know-How, about the role of scientist, men and women, in oil and gas sector from R&D to field work. In addition to understand the main problems that facing the scientists in such field and figuring out how to control such problems. Furthermore, the course helps to explore the potential of microorganisms in oil and gas from positive and negative aspects such as microbial influenced corrosion, biofilms, enhancement& treatment. The course gives many examples and case study about different situations, demonstrating the whole steps that are taken in appraising the limitations & importance of this industry. Moreover, this course prepares and get ready the biotechnological graduates to the Jobs-Market.